BindingDB

The first public molecular recognition database, BindingDB supports research, education and practice in drug discovery, pharmacology and related fields.

BindingDB contains 2.9M data for 1.2M Compounds and 9.3K Targets. Of those, 1,352K data for 627K Compounds and 4.5K Targets were curated by BindingDB curators. BindingDB is a FAIRsharing resource.

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9 articles for thisTarget

The following articles (labelled with PubMed ID or TBD) are for your review

PMID
Data
Article Title
Organization
Development of substrate analogue inhibitors for the human airway trypsin-like protease HAT.EBI
Philipps University Marburg
TMPRSS2 Inhibitor Discovery Facilitated through an EBI
University of Michigan
Enzyme inhibition as a potential therapeutic strategy to treat COVID-19 infection.EBI
Kingston University
Chinese Therapeutic Strategy for Fighting COVID-19 and Potential Small-Molecule Inhibitors against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2).EBI
South China Agricultural University
Potent Inhibition of SARS-CoV-2 nsp14 BDB
University of Montpellier
A TMPRSS2 inhibitor acts as a pan-SARS-CoV-2 prophylactic and therapeutic.BDB
University of British Columbia
 
Discovery of S-217622, a Non-Covalent Oral SARS-CoV-2 3CL Protease Inhibitor Clinical Candidate for Treating COVID-19BDB
Shionogi
The recent outbreaks of human coronaviruses: A medicinal chemistry perspective.BDB
University of Bonn
The androgen-regulated protease TMPRSS2 activates a proteolytic cascade involving components of the tumor microenvironment and promotes prostate cancer metastasis.BDB
Fred Hutchinson Cancer Research Center